HORDB

ID: hor004007
Uniprot ID: A0A8J5J8V2
Protein name: Pyrokinin
Gene name: NA
Organism: Homarus americanus (American lobster)
Family: Pyrokinin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Homarus (genus), Nephropidae (family), Nephropoidea (superfamily), Astacidea (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007165 signal transduction
GO CC: NA

Sequence: FSPRL
Length: 5
Propeptide: MESQYKSLLVSDRTTAEEVVELLLNCCNTPDNKCYYAIHEVESYCPPGVTVLLGDIVLLGDIVVLGHCSPGHCSPGVIVLLGSLFSWVIVLLGHCSPGVRRSPDYNDRMILPQERPLEVKAQWPRDRQAEFVFVLRRNMSQALSLRRLSLRTGDTKRPTVAGSQGEQTHFSPRLQWSQWLGTSWLPPPPSQKTAKTQDRINVLIIEEAVIDCTDVTPKMTTINRTATQGCKGALEVFNGTTSTSAINSQLHHNTSTRDSSTNTDRKTWSNTSTQTNVSKKFPRSASLPRDQNPSRDRQTEDYLTHSEK
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004007_AF2.pdb

hor004007_ESM.pdb

Mass:	69025	Formula:	C29H46N8O7
Absent amino acids:	ACDEGHIKMNQTVWY	Common amino acids:	FLPRS
pI:	10.55	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	2
Hydrophobicity:	-6	Boman Index:	-1042
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	78
Instability Index:	8080	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 18304551
Title: Mass Spectral Characterization of Peptide Transmitters/Hormones in the Nervous System and Neuroendocrine Organs of the American Lobster Homarus Americanus